DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy
L. A. Baldwin, N. Bartonicek, J. Yang, S. Z. Wu, N. Deng, D. L. Roden, C.-L. Chan, G. Al-Eryani, D. J. Zanker, B. S. Parker, A. Swarbrick, S. Junankar
This study uses DNA barcoding to track clonal evolution in breast cancer during metastasis and immunotherapy, finding ongoing immunoediting and identifying potential therapeutic targets.
bioRxiv · Jan 11, 2021Cancer Biology