APC/CFZR-1 Controls ZYG-1 Levels to Regulate Centrosome Assembly
J. C. Medley, J. R. DiPanni, L. Schira, B. Shaffou, B. Sebou, M. H. SONG
This study identifies ZYG-1 as a substrate of APC/CFZR-1 in C. elegans, showing that APC/CFZR-1 and SCFSlimb/βTrCP ubiquitin ligases cooperatively regulate ZYG-1 stability to control centrosome number.
bioRxiv · Aug 12, 2020 · PreprintCell Biology