Modifying Azithromycin to Mitigate Arrested Autophagy
R. D. Quarrington, S. Chen, S. A. Sapula, S. W. Liu, S. E. Lester, M. M. Miller, V. Munic Kos, B. T. Kopp, H. P. Jersmann, A. Blencowe, E. Roscioli
This paper shows azithromycin inhibits autophagy and presents a modified version, AZM-[O], that reduces this effect while retaining antimicrobial and immunomodulatory functions.
bioRxiv · Apr 25, 2024 · PreprintBiochemistry