Author

E. Roscioli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Blencowe· 1 shared A. Ciabattini· 1 shared A. D. McAinsh· 1 shared A. I. Thompson· 1 shared A. Kabanova· 1 shared A. R. Zelmer· 1 shared B. T. Kopp· 1 shared C. A. Smith· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Blencowe

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Modifying Azithromycin to Mitigate Arrested Autophagy

R. D. Quarrington, S. Chen, S. A. Sapula, S. W. Liu, S. E. Lester, M. M. Miller, V. Munic Kos, B. T. Kopp, H. P. Jersmann, A. Blencowe, E. Roscioli

This paper shows azithromycin inhibits autophagy and presents a modified version, AZM-[O], that reduces this effect while retaining antimicrobial and immunomodulatory functions.

bioRxiv · Apr 25, 2024 · PreprintBiochemistry

Anti-capsule human monoclonal antibodies protect against hypervirulent and pandrug-resistant Klebsiella pneumoniae

E. Roscioli, V. Zucconi Galli Fonseca, S. S. Bosch, I. Paciello, G. Maccari, G. Batani, S. Stazzoni, G. Cardinali, G. Tiseo, C. Giordano, Y. Shen, L. Capoccia, M. Ridelfi, M. Troisi, N. Manganaro, , R. Rappuoli

This study isolates human monoclonal antibodies against hypervirulent, pandrug-resistant Klebsiella pneumoniae and identifies capsule-specific antibodies as protective against bloodstream infection.

bioRxiv · Feb 14, 2024 · PreprintMicrobiology

Staphylococcus aureus Persistence in Osteocytes: Weathering the Storm of Antibiotics and Autophagy/Xenophagy

N. J. Gunn, A. R. Zelmer, S. P. Kidd, L. B. Solomon, D. Yang, E. Roscioli, G. J. Atkins

This study investigates how antibiotics and autophagy modulation affect intracellular Staphylococcus aureus persistence in osteocytes, finding that antibiotics inhibit autophagy but do not clear bacterial DNA.

bioRxiv · Oct 27, 2023 · PreprintMicrobiology

Ensemble-level organization of human kinetochores and evidence for distinct tension and attachment sensors

E. Roscioli, T. E. Germanova, C. A. Smith, P. A. Embacher, M. Erent, A. I. Thompson, N. J. Burroughs, A. D. McAinsh

The paper uses fluorescence localisation to study the organization of kinetochore proteins and identifies two mechanical sensors involved in monitoring attachment and tension.

bioRxiv · Jun 28, 2019Cell Biology