The aminoalkylindole, BML-190, negatively regulates chitosan synthesis via the cAMP/PKA1 pathway in Cryptococcus neoformans
B. T. Maybruck, W. C. Lam, C. Specht, M. X. G. Ilagan, M. J. Donlin, J. K. Lodge
This paper identifies BML-190 as a compound that reduces chitosan synthesis in Cryptococcus neoformans via the cAMP/PKA1 pathway, suggesting a potential new therapeutic target.
bioRxiv · Aug 29, 2019Microbiology