Author

B. Valkenburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Mercieca· 1 shared I. de Heer· 1 shared J. Aerts· 1 shared M. de Wit· 1 shared M. van Royen· 1 shared P. French· 1 shared P. Sillevis Smitt· 1 shared Y. Gao· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

D. Mercieca

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1 paper

Recent·Most cited

Effective Tyrosine Kinase Inhibitors result in the intracellular accumulation of EGFR and allows response prediction in patients

M. de Wit, Y. Gao, D. Mercieca, I. de Heer, B. Valkenburg, M. van Royen, J. Aerts, P. Sillevis Smitt, P. French

The paper shows that EGFR tyrosine kinase inhibitors (TKIs) cause intracellular EGFR accumulation only in specific mutation-TKI combinations, which predicts clinical response in patients.

bioRxiv · Oct 21, 2019 · PreprintCancer Biology