Author

M. van Royen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

P. French· 2 shared A. Ray Chaudhuri· 1 shared B. Valkenburg· 1 shared C. Lo· 1 shared C. Mukherjee· 1 shared D. Mercieca· 1 shared D. Wheeler· 1 shared E. Maria Manolika· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

P. French

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

SMARCAD1 Mediated Active Replication Fork Stability Maintains Genome Integrity

C. Lo, M. van Toorn, V. Gaggioli, M. Paes Dias, Y. Zhu, E. Maria Manolika, W. Zhao, M. van der Does, C. Mukherjee, J. Souto Goncalves, M. van Royen, P. French, J. Demmers, I. Smal, H. Lans, , N. Taneja

This study identifies SMARCAD1 as a critical factor for replication fork stability, showing its role in preventing genome instability and enhancing resistance to replication poisons.

bioRxiv · Oct 5, 2020Cell Biology

Effective Tyrosine Kinase Inhibitors result in the intracellular accumulation of EGFR and allows response prediction in patients

M. de Wit, Y. Gao, D. Mercieca, I. de Heer, B. Valkenburg, M. van Royen, J. Aerts, P. Sillevis Smitt, P. French

The paper shows that EGFR tyrosine kinase inhibitors (TKIs) cause intracellular EGFR accumulation only in specific mutation-TKI combinations, which predicts clinical response in patients.

bioRxiv · Oct 21, 2019 · PreprintCancer Biology