Author

B. vd Roest

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. van Hoeck· 1 shared Center for Personalized Cancer Treatment· 1 shared E. Cuppen· 1 shared E. Kuijk· 1 shared J. Martens· 1 shared M.-L. Yaspo· 1 shared N. Besselink· 1 shared P. Priestley· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. van Hoeck

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1 paper

Recent·Most cited

5-Fluorouracil treatment induces characteristic T>G mutations in human cancer

S. Christensen, B. vd Roest, N. Besselink, R. Janssen, S. Boymans, J. Martens, M.-L. Yaspo, P. Priestley, Center for Personalized Cancer Treatment, E. Kuijk, E. Cuppen, A. van Hoeck

This study shows that 5-FU treatment causes characteristic T>G mutations in cancer, similar to endogenous mutational signatures, and may increase secondary malignancy risk.

bioRxiv · Jun 25, 2019Cancer Biology