Author

J. Martens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. van Hoeck· 2 shared E. Cuppen· 2 shared A. Dolnik· 1 shared A. Krupp· 1 shared A. Serebrenik· 1 shared B. vd Roest· 1 shared B. Verhalen· 1 shared Center for Personalized Cancer Treatment· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

A. van Hoeck

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Community context influences the conjugation efficiency of E. coli

M. Bustamante, F. Koopman, J. Martens, J. K. Brons, J. DelaFuente, O. Kuipers, G. S. van Doorn, M. de Vos

The paper investigates how polymicrobial communities affect conjugation rates of uropathogenic E. coli in artificial urine medium, finding that Gram-positive enterococci enhance conjugation rates.

bioRxiv · Jan 30, 2024 · PreprintEcology

Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia

Y. Zhai, P. Singh, A. Dolnik, P. Brazda, N. Atlasy, N. del Gaudio, K. Dohner, H. Dohner, S. Minucci, J. Martens, L. Altucci, W. Megchelenbrink, L. Bullinger, H. G. Stunnenberg

This study uses longitudinal single-cell transcriptomics to analyze AML recurrence patterns, finding varying transcriptional changes between diagnosis and relapse that challenge the clonal evolution model.

bioRxiv · Jan 4, 2022 · PreprintCancer Biology

Pan-cancer landscape of homologous recombination deficiency

L. Nguyen, J. Martens, A. van Hoeck, E. Cuppen

This study develops a pan-cancer Classifier of Homologous Recombination Deficiency (CHORD) and identifies HRD frequency and genetic causes across multiple cancer types.

bioRxiv · Jan 13, 2020Cancer Biology

5-Fluorouracil treatment induces characteristic T>G mutations in human cancer

S. Christensen, B. vd Roest, N. Besselink, R. Janssen, S. Boymans, J. Martens, M.-L. Yaspo, P. Priestley, Center for Personalized Cancer Treatment, E. Kuijk, E. Cuppen, A. van Hoeck

This study shows that 5-FU treatment causes characteristic T>G mutations in cancer, similar to endogenous mutational signatures, and may increase secondary malignancy risk.

bioRxiv · Jun 25, 2019Cancer Biology

Polyomavirus T-Antigen Induces APOBEC3B Expression using a LXCXE-Dependent and TP53-Independent Mechanism

G. Starrett, A. Serebrenik, P. Roelofs, B. Verhalen, J. McCann, M. Jarvis, T. Stewart, E. Law, A. Krupp, M. Jiang, J. Martens, P. Span, E. Cahir-McFarland, R. Harris

This paper shows polyomavirus T-antigen induces APOBEC3B expression via the LXCXE motif without requiring TP53 inhibition, linking RB/E2F axis activation to APOBEC3B upregulation in virus-infected cells.

bioRxiv · May 2, 2018Microbiology