A cGAS-mediated IFN-I response in human CD4+ T cells depends on productive infection and is conserved over HIV types and strains
M. Janevska, T. Cammaert, E. Naessens, B. Verhasselt
This study shows that HIV-1 and HIV-2 induce a cGAS-dependent IFN-I response in CD4+ T cells, which requires productive infection and is conserved across HIV types.
bioRxiv · Jan 12, 2024 · PreprintMicrobiology