The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells
Fugui Niu, Peng Han, Jian Zhang, Yuanchu She, Lixin Yang, Jun Yu, Mengru Zhuang, Kezhen Tang, Yuwei Shi, Baisheng Yang, Chunqiao Liu, Bo Peng, Sheng‐Jian Ji
This study shows YTHDF2 negatively regulates RGC dendrite development and maintenance, with its knockout improving visual acuity and protecting against glaucoma in mice.
eLife · Feb 18, 2022Peer-reviewedNeuroscience