BiochemistryJournal of Biological ChemistryPeer-reviewed
Targeting the Protein-Protein Interaction Between the CDC37 Co-Chaperone and Client Kinases by an Allosteric RAF Dimer Breaker
Alison Yu, Shrhea Banerjee, Sravani Malasani…·Zhihong Wang
This study investigates Braftide's dual effect on RAF dimer disruption and CDC37-client kinase interaction, showing proteasomal degradation and therapeutic potential.
2 citations