Author

Sravani Malasani

Rowan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Zhihong WangiD· 3 shared Shrhea BanerjeeiD· 2 shared Alison YuiD· 1 shared Bamidele Toheeb Towolawi· 1 shared Bamidele Towolawi· 1 shared Colin Christoff· 1 shared Govinda R. Navale· 1 shared Maria Celeste Lopez Vasquez· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBiochemistry

Zhihong WangORCID

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Author profile →

4 papers

Recent·Most cited

GNG2-MRAS interaction regulates SHOC2-dependent RAF activation and MAPK signaling

Govinda R. Navale, Bamidele Towolawi, Colin Christoff, Sravani Malasani, Zhiwei Liu, Zhihong Wang

This study identifies GNG2 as an inhibitor of the SMP complex by binding MRAS, disrupting its assembly and inhibiting MAPK signaling.

bioRxiv · Nov 3, 2026 · PreprintBiochemistry

Kinetic Signatures of RAS-BRAF Engagement Reveal Isoform Selectivity, Oncogenic Amplification, and Mutation-Dependent Inhibitor Resistance

Sravani Malasani, Zhihong Wang

This study identifies kinetic differences in RAS-BRAF engagement between KRAS and NRAS, showing how oncogenic mutations and inhibitor sensitivity are influenced by these dynamics.

FEBS Journal · Oct 27, 2026Peer-reviewedBiophysics

Divergent CRD-Dependent Mechanisms Govern RAS Isoform-Selective Recruitment of CRAF and ARAF

Shrhea Banerjee, Sravani Malasani, Shriti Banerjee, Maria Celeste Lopez Vasquez, Shane McSorley, Zhihong Wang

This study identifies divergent CRD-dependent mechanisms by which RAS isoforms selectively recruit CRAF and ARAF, revealing how the CRD modulates RAS affinity and RAF activation.

Protein Science · Jul 9, 2026Peer-reviewedBiochemistry

Targeting the Protein-Protein Interaction Between the CDC37 Co-Chaperone and Client Kinases by an Allosteric RAF Dimer Breaker

Alison Yu, Shrhea Banerjee, Sravani Malasani, Bamidele Toheeb Towolawi, Zhiwei Liu, Zhihong Wang

This study investigates Braftide's dual effect on RAF dimer disruption and CDC37-client kinase interaction, showing proteasomal degradation and therapeutic potential.

Journal of Biological Chemistry · Dec 9, 2025Peer-reviewedBiochemistry