Structural Interactions of Ankyrin B with NrCAM and β2 Spectrin
Venkat R. Chirasani, Victoria A. Haberman, Erik N. Oldre, Barrett D. Webb, Ernest B. Pereira, Wonsuk Yang, Patricia F. Maness
The paper uses AlphaFold to model AnkB interactions with NrCAM and β2-Spectrin, identifies critical residues, and shows how ASD mutations disrupt these interactions and neuronal function.
Journal of Biological Chemistry · Oct 31, 2025Peer-reviewedNeuroscience