Author

Justin E. Sperringer

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 2 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Patricia F. ManessiD· 4 shared Bryce W. DuncaniD· 3 shared Kelsey E. Murphy· 3 shared Elliott V. Wyatt· 2 shared Erin Y. Zhang· 2 shared Barrett D. Webb· 1 shared David LutziD· 1 shared Erik N. OldreiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersNeuroscience

Patricia F. ManessORCID

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4 papers

Recent·Most cited

Regulation of Perisomatic Synapses from Cholecystokinin Basket Interneurons through NrCAM and Ankyrin B

Erik N. Oldre, Barrett D. Webb, Justin E. Sperringer, Patricia F. Maness

The paper investigates the role of NrCAM and Ankyrin B in establishing synaptic contacts between CCK basket interneurons and pyramidal neurons in the mouse medial prefrontal cortex.

Current Research in Neurobiology · Apr 8, 2025Peer-reviewedNeuroscience

Ankyrin B Promotes Developmental Spine Regulation in the Mouse Prefrontal Cortex

Kelsey E. Murphy, Bryce W. Duncan, Justin E. Sperringer, Erin Y. Zhang, Victoria A. Haberman, Elliott V. Wyatt, Patricia F. Maness

This study identifies AnkB's role in dendritic spine regulation in the mouse prefrontal cortex and links it to potential molecular mechanisms in ASD.

Cerebral Cortex · Aug 26, 2023Peer-reviewedNeuroscience

The L1 Cell Adhesion Molecule Constrains Dendritic Spine Density through Ankyrin Binding in Pyramidal Neurons of the Mouse Cerebral Cortex

Kelsey E. Murphy, Sarah D. Wade, Justin E. Sperringer, Vishwa Mohan, Bryce W. Duncan, Yubin Pak, David Lutz, Melitta Schachner, Patricia F. Maness

This study identifies L1 cell adhesion molecule's role in regulating dendritic spine density via Ankyrin binding in mouse pyramidal neurons, showing increased spine density in L1 mutants and impaired spine pruning in response to Semaphorins.

bioRxiv · May 16, 2022 · PreprintNeuroscience

Doublecortin-like kinase 1 (DCLK1) Facilitates Dendritic Spine Growth of Pyramidal Neurons in Mouse Prefrontal Cortex

Kelsey E. Murphy, Erin Y. Zhang, Elliott V. Wyatt, Justin E. Sperringer, Bryce W. Duncan, Patricia F. Maness

This study shows that DCLK1 promotes dendritic spine growth and maturation in mouse prefrontal cortex pyramidal neurons through interactions with NrCAM and microtubules.

bioRxiv · May 13, 2022Neuroscience