Venkat R. Chirasani

This study identifies an HIV-1 Tat variant (R52W) that reduces transcriptional activity, potentially contributing to viral persistence during ART.

This study identifies APOE interacting with COX-2 on lipid droplets, showing APOE3 promotes and APOE4 suppresses COX-2 activity and prostaglandin production.

This study shows that Catestatin improves heart metabolic flexibility by enhancing mitochondrial structure and function through binding to ATP synthase.

The paper uses AlphaFold to model AnkB interactions with NrCAM and β2-Spectrin, identifies critical residues, and shows how ASD mutations disrupt these interactions and neuronal function.

The paper investigates the functional roles of the N-terminal intrinsically disordered region of Bloom Syndrome helicase in Drosophila by deleting conserved regions and assessing their impact on DNA repair and meiotic processes.