Transcriptional pathobiology and multi-omics predictors for Parkinson's disease
Ruifeng Hu, Ruoxuan Wang, Jie Yuan, Zechuan Lin, Elizabeth D. Hutchins, Barry Landin, Zhixiang Liao, Ganqiang Liu, Clemens R. Scherzer, Xianjun Dong
This study identifies 1,111 PD-associated RNAs in blood and develops a multi-omics model with AUC 0.89 for PD diagnosis, offering insights into pathobiology and potential clinical applications.
bioRxiv · Jun 18, 2024 · PreprintNeuroscience