Ruifeng Hu

This study shows that SMCHD1's weak DNA binding is essential for its chromatin retention and function, revealing how DNA binding affects its localization and gene repression.

This paper develops a biophysical platform to deliver electromechanical stimulation to engineered cardiac tissues and shows that synchronized stimulation increases contractile force.

This study identifies 1,111 PD-associated RNAs in blood and develops a multi-omics model with AUC 0.89 for PD diagnosis, offering insights into pathobiology and potential clinical applications.