Stochastic activation and bistability in a Rab GTPase regulatory network.
Urban Bezeljak, Hrushikesh Loya, Beata Kaczmarek, Timothy E. Saunders, Martin Loose
The paper studies a minimal Rab5 activation network to show how positive feedback leads to bistable switching and how controlling inactive Rab5 populations shapes network responses.
Proceedings of the National Academy of Sciences · Mar 11, 2020Peer-reviewedSystems Biology