Hrushikesh Loya

Genome-wide genealogies reveal deep admixtures forming modern humans

This paper introduces GhostBuster, a method to detect unsampled admixture events in human history using genome-wide genealogies, revealing multiple back-to-Africa migrations and deep ancestral lineages.

Fast variance component analysis using large-scale ancestral recombination graphs

The paper introduces ARG-RHE, a method to estimate heritability and perform association testing using ancestral recombination graphs, showing improved results over imputation alone.

Stochastic activation and bistability in a Rab GTPase regulatory network.

The paper studies a minimal Rab5 activation network to show how positive feedback leads to bistable switching and how controlling inactive Rab5 populations shapes network responses.