Subsynaptic positioning of AMPARs by LRRTM2 controls synaptic strength
Austin M. Ramsey, Ai‐Hui Tang, Tara A. LeGates, Xu‐Zhuo Gou, Beatrice E. Carbone, Scott M. Thompson, Thomas Biederer, Thomas A. Blanpied
This study shows that LRRTM2 controls AMPAR subsynaptic positioning, which dynamically regulates synaptic strength by affecting receptor clustering near presynaptic release sites.
Science Advances · Aug 20, 2021Peer-reviewedNeuroscience