An imbalance of naive and effector T-cell phenotypes in early type 1 diabetes across conventional and regulatory subsets
Veronika Niederlová, Aleš Neuwirth, Vít Neuman, Juraj Michalik, Bela Charvatova, Martin Modrák, Zdenĕk Šumnı́k, Ondřej Štěpánek
The paper identifies reduced effector and cytotoxic T-cell gene expression in early type 1 diabetes across multiple T-cell subsets using single-cell transcriptomics and flow cytometry.
Nature Communications · Dec 11, 2025Peer-reviewedImmunology