LPS O-antigen polysaccharide length impacts outer membrane permeability of enteric gram-negative bacteria
Kerrie L. May, Tatsuya Akiyama, Bella G. Parker, Minsu Kim, Marcin Grabowicz
This study shows that longer O-antigen polysaccharides on LPS in E. coli and Shigella flexneri weaken the outer membrane barrier, increasing antibiotic susceptibility.
mBio · Nov 5, 2025Peer-reviewedMicrobiology