Minsu Kim

This study shows bacteriostatic antibiotics induce physiological stress in E. coli, leading to cell lysis and lethality, challenging the view that they are less effective than bactericidal drugs.

The paper identifies sigmaE as a key regulator of colistin heteroresistance in Enterobacter cloacae, showing that multiple regulatory systems are required for this resistance.

The paper shows that initial spatiotemporal deficits in microbial populations can become competitive advantages during collective expansion through nonlinear density-dependent feedback.

This study shows that heteroresistance evolves under treatment interruptions in E. coli, using phenotypic flexibility to maintain resistance with minimal fitness cost.

This study shows that longer O-antigen polysaccharides on LPS in E. coli and Shigella flexneri weaken the outer membrane barrier, increasing antibiotic susceptibility.

The paper introduces the DnD assay to detect hidden antibiotic resistance mechanisms with high resolution, demonstrating its ability to quantify viable cells over eight orders of magnitude and classify clinical isolates.

The paper shows that glucose availability increases fosfomycin resistance in Enterobacter cloacae by altering GlpT expression and enhancing fosA gene activity.

This study shows that Sonic hedgehog signaling from cortical neurons regulates astrocyte development and synaptic connectivity during cortical circuit formation.

This paper quantifies optimal parameters for 1300-nm three-photon calcium imaging in mice to balance fidelity and tissue heating.