Multiscale 3D whole joint cellular and molecular mapping dissects the relationship between structure and pain
Chen Peng, Jiaxin Chai, Abirami Soundararajan, R. Glenn Hepfer, Benjamin Kheyfets, Jiaxin Hu, Ishraq Alshanqiti, Swarnalakshmi Raman, Ikue Tosa, Jun Tae Huh, Matthew Yee, Brooke J. Damon, Shangping Wang, Yu Shin Kim, Man‐Kyo Chung, , Hai Yao
This paper introduces a method for 3D multiscale analysis of joints, revealing neurovascular changes linked to pain and degeneration across species and tissues.
bioRxiv · Aug 23, 2025 · PreprintBioengineering