Author

Jiaxin Chai

Clemson University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Hai YaoiD· 3 shared Abirami Soundararajan· 1 shared Benjamin Kheyfets· 1 shared Brooke Damon· 1 shared Brooke J. Damon· 1 shared Chen PengiD· 1 shared Farhad AhmadiiD· 1 shared Hainan LangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioengineering

Hai YaoORCID

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Author profile →

3 papers

Recent·Most cited

A Novel Central-Peripheral Interface: The Auditory Nerve Glial Transition Zone Exhibits Enhanced Age-Related Immune and Glial Cell Dysfunction

Shelby A. Payne, Haley R Anderson, Isaac M. Brown, Jiaxin Chai, Peng Chen, Hai Yao, Jeremy L. Barth, Hainan Lang

This study identifies the auditory nerve glial transition zone as a critical site of age-related immune and glial dysfunction contributing to hearing loss.

Frontiers in Immunology · Aug 7, 2026Peer-reviewedNeuroscience

Multiscale Biomechanical and Electrophysiological Modeling of Nociceptive Activation in Musculoskeletal Joint Disorders: Insights from the Temporomandibular Joint

J Chen, Shuchun Sun, Farhad Ahmadi, P G Chen, Jiaxin Chai, Jichao Zhao, Brooke Damon, Konstantinia Almpani, Janice Lee, Hai Yao

This study develops a multiscale computational model linking TMJ structural changes to nociceptive activation by integrating biomechanics, neural morphology, and electrophysiology.

bioRxiv · Jul 22, 2026 · PreprintBioengineering

Multiscale 3D whole joint cellular and molecular mapping dissects the relationship between structure and pain

Chen Peng, Jiaxin Chai, Abirami Soundararajan, R. Glenn Hepfer, Benjamin Kheyfets, Jiaxin Hu, Ishraq Alshanqiti, Swarnalakshmi Raman, Ikue Tosa, Jun Tae Huh, Matthew Yee, Brooke J. Damon, Shangping Wang, Yu Shin Kim, Man‐Kyo Chung, , Hai Yao

This paper introduces a method for 3D multiscale analysis of joints, revealing neurovascular changes linked to pain and degeneration across species and tissues.

bioRxiv · Aug 23, 2025 · PreprintBioengineering