Central inhibition of P2Y12R differentially regulates survival and neuronal loss in MPTP-induced Parkinsonism in mice
András Iring, Adrián Tóth, Mária Baranyi, Lilla Otrokocsi, László Módis, Flóra Gölöncsér, Bernadett Varga, Tibor Hortobágyi, Dániel Bereczki, Ádám Dénes, Beáta Sperlágh
This study investigates the role of P2Y12R in Parkinson's disease progression in mice, showing that its inhibition can protect against neurodegeneration and neuroinflammation.
bioRxiv · Feb 3, 2021 · PreprintNeuroscience