AMPK activation prevents HCC development through inhibition of HNF4a activity
Zhen Sun, Bernard Linares, Cassidy Urdiales, Fiyad Al-sarmi, Nagireddy Putluri, Jeanine L. Van Nostrand
This study shows that AMPK activation prevents HCC by inhibiting HNF4a activity, using genetic and pharmacological models.
bioRxiv · May 16, 2025 · PreprintCancer Biology