Acto-myosin cross-bridge stiffness depends on the nucleotide state of the myosin II
Tianbang Wang, Bernhard Brenner, Arnab Nayak, Mamta Amrute-Nayak
The paper compares the stiffness of slow and fast myosin II isoforms during the ATPase cycle, finding that the AM.ADP state has lower stiffness than the rigor state, affecting muscle contraction speed and force.
Nano Letters · Oct 14, 2020Peer-reviewedBiophysics