Arnab Nayak

The paper uses single-molecule techniques to reveal two distinct myosin cycles with different kinetics and stroke sizes affected by mavacamten and omecamtiv mecarbil.

This study investigates the molecular mechanism of cardiac myosin dysfunction caused by the A57D mutation in MLC1v using single-molecule analysis and computational modeling.

This study shows Sorafenib causes muscle wasting by disrupting chromatin regulators, leading to transcriptional changes and impaired muscle function.

The paper compares the stiffness of slow and fast myosin II isoforms during the ATPase cycle, finding that the AM.ADP state has lower stiffness than the rigor state, affecting muscle contraction speed and force.