Cross-species Study of Canine and Human Peripheral Nerve Sheath Tumors: Clinical and Molecular Perspectives
Jace P. Landry, Angela D. Bhalla, Sharon M. Landers, Rossana Lazcano, Lindsay A. Parker, Tasha M. Miller, Noelle Niemi, Heather Lyu, Heather A. Lillemoe, Emily Zhi-Yun Keung, Christopher P. Scally, Christina Lynn Roland, Kelly K. Hunt, John Mark Slopis, Ian E. McCutcheon, , Keila E. Torres
This study compares canine and human peripheral nerve sheath tumors, finding that H3K27me3 loss and H3K27ac gain drive tumor progression in both species.
bioRxiv · Jul 29, 2026 · PreprintCancer Biology