Time-on-task-related decrements in performance in the rodent continuous performance test are not caused by physical disengagement from the task
Ye Li, Thomas van Kralingen, Megan Masi, Brandon Villanueva Sanchez, Beyonca Mitchell, Joshua Johnson, Jorge A. Miranda-Barrientos, Jason J. Rehg, Keri Martinowich, Gregory V. Carr
This study shows that performance decline in the rodent Continuous Performance Test (rCPT) over time is due to vigilance decrements, not physical disengagement, and amphetamine improves performance without affecting task engagement.
NPP—Digital Psychiatry and Neuroscience · Feb 13, 2025Peer-reviewedNeuroscience