Non-catalytic regulation of 18S rRNA methyltransferase DIMT1 in acute myeloid leukemia
Yulia Gonskikh, Julian Stoute, Hui Shen, Krista A. Budinich, Bianca Y. Pingul, Kollin C. Schultz, Heidi E. Elashal, Ronen Marmorstein, Junwei Shi, Kathy Fange Liu
This study shows that DIMT1's non-catalytic function is essential for AML proliferation and identifies a target region for therapeutic intervention.
bioRxiv · Mar 18, 2023 · PreprintMolecular Biology