PEG400 regulates Falcipain 2 activity through an unprecedented allosteric mechanism
Bikram Nath, Subhoja Chakraborty, Sampa Biswas
This study reveals that PEG400 regulates Falcipain-2 activity through an allosteric mechanism, inhibiting small peptide substrates but enhancing hemoglobin degradation.
bioRxiv · Oct 29, 2025 · PreprintBiochemistry