Efficient generation of epitope-targeted de novo antibodies with Germinal
Luis Santiago Mille, Claudia L. Driscoll, John N. Wang, Haoyu Dai, Talal Widatalla, Jim L. Zhang, Xiaowei Zhang, Bing Rao, Liang Feng, Brian Hie, Xiaojing J. Gao
Germinal is a generative pipeline that designs functional antibodies with nanomolar binding affinities using minimal experimental testing.
bioRxiv · Sep 19, 2025 · PreprintSynthetic Biology