Liang Feng

The paper identifies 90 structurally distinct STAND NTPase families in bacteria and archaea that recognize phage proteins, revealing their role in antiviral defense.

The paper identifies proteolytic activation mechanisms in prokaryotic antiviral defense modules and shows their functional diversity and convergence with stress responses.

Germinal is a generative pipeline that designs functional antibodies with nanomolar binding affinities using minimal experimental testing.

This paper introduces a method to predict multiple protein conformations using entropy guidance, achieving high accuracy for membrane proteins.