Author

Björn Hartleben

Medizinische Hochschule Hannover

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:simulation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Andreas ButtenschöniD· 1 shared Dirk DrasdoiD· 1 shared Emma Wang· 1 shared Heiner WedemeyeriD· 1 shared Jan Georg HengstleriD· 1 shared Jieling ZhaoiD· 1 shared Johannes Georg BodeiD· 1 shared Julia HeldiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Andreas ButtenschönORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 9, 2026

Liver biopsy confirms precise and efficient correction of SERPINA1 after in vivo Base Editing in a Patient with Alpha-1 Antitrypsin Deficiency

Simon Alexander Krooss, Taihua Yang, Qinggong Yuan…·Michael Ott

Liver biopsy after PI*ZZ gene correction therapy reveals efficient and accurate base editing.

DOI 10.64898/2026.06.01.26354551

humanDNA methylation

𝕏 PostBluesky

Systems BiologybioRxivPreprintJul 31, 2025

The interplay between biomechanics and cell kinetics explains the spatial pattern in liver fibrosis

Jieling Zhao, Seddik Hammad, Mathieu de Langlard…·Dirk Drasdo

This paper develops a digital twin model to simulate liver fibrosis patterns, showing that ECM distribution results from cell death zones and biomechanical compression.

2 citations

mousesimulation

𝕏 PostBluesky