Dirk Drasdo

The interplay between biomechanics and cell kinetics explains the spatial pattern in liver fibrosis

This paper develops a digital twin model to simulate liver fibrosis patterns, showing that ECM distribution results from cell death zones and biomechanical compression.

Open Benchmarking for Cell-Based Multiscale Models: Lessons from a Community Initiative

This paper presents a community-driven benchmarking initiative for cell-based multiscale models, highlighting variations in tool implementations and advocating for standardized benchmarks and interoperability.

Quantitative agent-based modeling reveals mechanical stress response of growing tumor spheroids is predictable over various growth conditions and cell lines

The paper develops an agent-based model to predict tumor spheroid growth under mechanical stress across different conditions and cell lines.