Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex
Nelson Johansen, Niklas Kempynck, Nathan R. Zemke, Saroja Somasundaram, Seppe De Winter, Marcus J. Hooper, Deepanjali Dwivedi, Ruchi Lohia, Fabien Wehbe, Bocheng Li, Darina Abaffyová, Ethan J. Armand, Julie De Man, Eren Can Ekşi, Nikolai Hecker, , Trygve E. Bakken
The paper evaluates computational methods for predicting cell type-specific enhancers in the mouse cortex using in vivo validation data and finds that open chromatin and sequence models improve prediction accuracy.
Cell Genomics · May 21, 2025Peer-reviewedGenomics