Ruchi Lohia

The blobulator: a toolkit for identification and visual exploration of hydrophobic modularity in protein sequences

The blobulator toolkit identifies and visualizes hydrophobic modules in protein sequences using the blobulation algorithm, with applications across different protein types.

Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex

The paper evaluates computational methods for predicting cell type-specific enhancers in the mouse cortex using in vivo validation data and finds that open chromatin and sequence models improve prediction accuracy.

A global high-density chromatin interaction network reveals functional long-range and trans-chromosomal relationships

The paper creates a high-density chromatin interaction network across species by integrating 3C experiments, showing improved prediction of coexpression and eQTL for long-range and trans chromatin contacts.

Contiguously-hydrophobic sequences are functionally significant throughout the human exome

The paper examines the relationship between contiguous hydrophobic sequences and functional impact of SNPs, finding strong correlations with disease association and selective constraint.