Fabien Wehbe

This study identifies how aging impairs colonic regeneration in mice by promoting a fetal-like epithelial state through sustained IFNγ signaling.

The paper evaluates computational methods for predicting cell type-specific enhancers in the mouse cortex using in vivo validation data and finds that open chromatin and sequence models improve prediction accuracy.

This paper introduces scIDST, a weakly-supervised deep learning method to infer disease progressive stages in single-cell transcriptomics, revealing disease-relevant gene expression patterns not detectable by standard comparisons.