Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis
Cerys S Manning, Veronica Biga, James Boyd, Jochen Kursawe, Bodvar Ymisson, David G. Spiller, Christopher M. Sanderson, Tobias Galla, Magnus Rattray, Nancy Papalopulu
The paper uses live imaging and mathematical modeling to show HES5 protein dynamics correlate with cell-state transitions and fate decisions in murine neurogenesis.
Nature Communications · Jun 27, 2019Peer-reviewedDevelopmental Biology