Automated leg tracking reveals distinct conserved gait and tremor signatures in Drosophila models of Parkinson’s Disease and Spinocerebellar ataxia 3
Shuang Wu, Kah Junn Tan, Lakshmi Narasimhan Govindarajan, James Charles Stewart, Lin Gu, Joses Ho, Malvika Katarya, Boon Hui Wong, Eng‐King Tan, Daiqin Li, Adam Claridge‐Chang, Camilo Libedinsky, Li Cheng, Sherry Shiying Aw
The paper develops FLLIT, a machine-learning tool for automated leg tracking in Drosophila, revealing distinct gait and tremor signatures in PD and SCA3 models.
PLoS Biology · Jun 27, 2019Peer-reviewedNeuroscience