Function-specific epistasis shapes evolutionary trajectories towards antibiotic resistance
Gabriela Petrungaro, Theresa Fink, Booshini Fernando, Gerrit Ansmann, Tobias Bollenbach
This study shows that function-specific epistasis shapes antibiotic resistance evolution, with some genetic backgrounds leading to novel resistance trajectories and slower resistance development.
Nature Communications · Jul 28, 2026Peer-reviewedEvolutionary Biology