Gerrit Ansmann

Ultrasensitive fitness costs arise from membrane proteome displacement under protein overexpression

The paper quantifies fitness costs of protein overexpression in E. coli, showing growth collapse due to membrane proteome displacement, not translocation pathway saturation.

Function-specific epistasis shapes evolutionary trajectories towards antibiotic resistance

This study shows that function-specific epistasis shapes antibiotic resistance evolution, with some genetic backgrounds leading to novel resistance trajectories and slower resistance development.

Trace elements increase reproducibility of microbial growth

This study shows that adding trace elements to chemically defined media reduces variability in microbial growth experiments, supporting their routine use for more reproducible results.