MEST inhibits ciliary sphingomyelin synthesis to promote tendon stem/progenitor cells osteochondrogenesis in traumatic heterotopic ossification
Bowen Lai, Yuan Gao, Jianquan Zhao, Zhilong Zestel Shen, Rui Gao, Heng Jiang, Xuhui Zhou
This study identifies MEST's role in promoting tHO by inhibiting ciliary sphingomyelin synthesis and enhancing Hh signaling in TSPCs.
Genes & Diseases · Mar 1, 2026Peer-reviewedMolecular Biology