Schizophrenia-associated somatic copy number variants from 12,834 cases reveal contribution to risk and recurrent, isoform-specific NRXN1 disruptions
Eduardo A. Maury, Maxwell A. Sherman, Giulio Genovese, Thomas G. Gilgenast, Tushar Kamath, S.J. Burris, Prashanth Rajarajan, Erin K. Flaherty, Schahram Akbarian, Andrew J. Chess, Steven A. McCarroll, Po‐Ru Loh, Jennifer E. Phillips‐Cremins, Kristen Brennand, Evan Z. Macosko, , Brandon K. Wormley
This study identifies somatic copy number variants (sCNVs) in schizophrenia cases, revealing their contribution to risk and specific NRXN1 disruptions.
Cell Genomics · Jul 6, 2023Peer-reviewedGenetic & Genomic Medicine