Endothelial Cell Autophagy Suppresses Metastasis In Mouse Mammary and Pancreatic Neuroendocrine Tumor Models
Nancy Leon-Rivera, Brayden Chin, Ashley Quintana, Sofı́a Bustamante Eguiguren, Anthony Camilo Gacasan, Monica Nanni, Jayanta Debnath, Teresa Monkkonen
This study shows that endothelial cell autophagy reduces metastasis in mouse breast and pancreatic neuroendocrine tumor models by delaying tumor growth and increasing apoptosis.
bioRxiv · Jan 29, 2026 · PreprintCancer Biology