Author

Sofı́a Bustamante Eguiguren

University of California, San FranciscoORCID 0000-0002-4485-1494Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Anthony Camilo GacasaniD· 1 shared Ashley Quintana· 1 shared Brayden Chin· 1 shared Edward M. JenkinsiD· 1 shared Jake BurtoniD· 1 shared Jayanta DebnathiD· 1 shared Jesús A. Siller‐FarfániD· 1 shared Jose Cabezas-CaballeroiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Anthony Camilo GacasanORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 29, 2026

Endothelial Cell Autophagy Suppresses Metastasis In Mouse Mammary and Pancreatic Neuroendocrine Tumor Models

Nancy Leon-Rivera, Brayden Chin, Ashley Quintana…·Teresa Monkkonen

This study shows that endothelial cell autophagy reduces metastasis in mouse breast and pancreatic neuroendocrine tumor models by delaying tumor growth and increasing apoptosis.

1 citation

mousebulk RNA-seq

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ImmunologybioRxivPreprintJan 6, 2025

Optimising CAR-T cell sensitivity by engineering matched extracellular sizes between CAR/antigen and CD2/CD58 adhesion complexes

Jake Burton, Jesús A. Siller‐Farfán, Violaine André…·Omer Dushek

The antigen sensitivity of CAR-T cells can be tuned to match the sensitivity of TCR-T cells by varying the relative extracellular size of CAR/antigen and CD2/CD58 complexes.

2 citations

humanproteomics

𝕏 PostBluesky