Author

Brendan D. Galvin

10X Genomics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:genome assembly· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Haynes HeatoniD· 2 shared Sofia Kyriazopoulou-Panagiotopoulou· 2 shared Aaron R. CooperiD· 1 shared Adam Barner· 1 shared Adam J. LoweiD· 1 shared Adrian N. Fehr· 1 shared Allyson J. MerrelliD· 1 shared Álvaro Martínez BarrioiD· 1 shared

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2019-2025 · peak 2/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Haynes HeatonORCID

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3 papers

Recent·Most cited

DINOcell: Learning Generalizable Perturbation Effects through Self-Distillation

Jonathan Li, Nilgun Tasdemir, Sofia Kyriazopoulou-Panagiotopoulou, Sophie Xu, Allyson J. Merrell, Josephine Susanto, Ashley A. Cass, David DeTomaso, Holly Steach, Julie C. Chow, Li Wang, Neal G. Ravindra, Aram Kang, Grace X. Y. Zheng, Mary Chua, , Amaro N Taylor-Weiner

DINOcell predicts cellular responses to perturbations using self-distillation in single-cell transcriptomics, outperforming baselines for single and combination gene effects.

bioRxiv · Dec 19, 2025 · PreprintBioinformatics

Resolving the Full Spectrum of Human Genome Variation using Linked-Reads

Patrick Marks, Sarah Garcia, Álvaro Martínez Barrio, Kamila Belhocine, Jorge Bernate, Rajiv Bharadwaj, Keith P. Bjornson, Claudia Catalanotti, Josh Delaney, Adrian N. Fehr, Ian T. Fiddes, Brendan D. Galvin, Haynes Heaton, Jill Herschleb, Christopher M. Hindson, , Deanna M. Church

This paper introduces Linked-Reads as a method to comprehensively analyze genome variation, showing it can detect both small and large variants and reconstruct haplotypes more effectively than short-read sequencing.

Genome Research · Apr 1, 2019Peer-reviewedGenomics

A High-Quality De Novo Genome Assembly from a Single Mosquito using PacBio Sequencing

Sarah B. Kingan, Haynes Heaton, Juliana Cudini, Christine C. Lambert, Primo A. Baybayan, Brendan D. Galvin, Richard Michael Durbin, Jonas Korlach, Mara Lawniczak

This paper presents a high-quality de novo genome assembly of a single Anopheles coluzzii mosquito using a modified PacBio protocol, achieving high contiguity and completeness with low DNA input.

Genes · Jan 18, 2019Peer-reviewedGenomics